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miR-29 is an important driver of aging-related phenotypes

Abstract Aging is a consequence of complex molecular changes, but whether a single microRNA (miRNA) can drive aging remains unclear. A miRNA known to be upregulated during both normal and premature aging is miR-29. We find miR-29 to also be among the top miRNAs predicted to drive aging-related gene...

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Κύριοι συγγραφείς: Vijay Swahari, Ayumi Nakamura, Emilie Hollville, Yu-Han Hung, Matt Kanke, C. Lisa Kurtz, Xurde M. Caravia, David Roiz-Valle, Shenghui He, Janakiraman Krishnamurthy, Sahil Kapoor, Varun Prasad, Cornelius Flowers, Matt Beck, Jeanette Baran-Gale, Norman Sharpless, Carlos López-Otín, Praveen Sethupathy, Mohanish Deshmukh
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Portfolio 2024-08-01
Σειρά:Communications Biology
Διαθέσιμο Online:https://doi.org/10.1038/s42003-024-06735-z
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