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Gout management using uricase and sodium citrate hollow mesoporous nanomotors

Abstract Uricase (UOx)-based gout treatments are generally limited due in part to the accumulation of H2O2 in an arthrosis environment characterized by a sluggish metabolism. Here we develop a self-cascade nanomotor with high efficiency toward simultaneous uric acid (UA) degradation and H2O2 elimina...

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主要な著者: Lu Liu, Xiurong Li, Yongxian Chen, Junbin Gao, Yuejun Jiang, Yicheng Ye, Peng Wang, Fei Peng, Yingfeng Tu
フォーマット: Artigo
言語:Inglês
出版事項: Nature Portfolio 2025-03-01
シリーズ:Nature Communications
オンライン・アクセス:https://doi.org/10.1038/s41467-025-56100-9
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