Impairment of immunoproteasome function by β5i/LMP7 subunit deficiency results in severe enterovirus myocarditis.
Proteasomes recognize and degrade poly-ubiquitinylated proteins. In infectious disease, cells activated by interferons (IFNs) express three unique catalytic subunits β1i/LMP2, β2i/MECL-1 and β5i/LMP7 forming an alternative proteasome isoform, the immunoproteasome (IP). The in vivo function of IPs in...
Furkejuvvon:
| Váldodahkkit: | , , , , , , , , , , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Public Library of Science (PLoS)
2011-09-01
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| Ráidu: | PLoS Pathogens |
| Liŋkkat: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21909276/?tool=EBI |
| Fáddágilkorat: |
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