Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain

Abstract Background Osteoarthritis is increasingly recognized as the result of a complex interplay between inflammation, chrondrodegeneration, and pain. Joint mast cells are considered to play a key role in orchestrating this detrimental triad. ALIAmides down-modulate mast cells and more generally h...

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Detalhes bibliográficos

Principais autores:	Marika Cordaro, Rosalba Siracusa, Daniela Impellizzeri, Ramona D’ Amico, Alessio Filippo Peritore, Rosalia Crupi, Enrico Gugliandolo, Roberta Fusco, Rosanna Di Paola, Carlo Schievano, Salvatore Cuzzocrea
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2019-11-01
coleção:	Arthritis Research & Therapy
Assuntos:	Osteoarthritis Pain Mast cells ALIAmides N-palmitoyl-D-glucosamine Palmitoylethanolamide
Acesso em linha:	https://doi.org/10.1186/s13075-019-2048-y
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