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Mitochondrial sirtuins: Energy dynamics and cancer metabolism

ABSTRACT: Mitochondria are pivotal for energy regulation and are linked to cancer. Mitochondrial sirtuins, (Sirtuin) SIRT3, SIRT4, and SIRT5, play crucial roles in cancer metabolism. This review explores their impact on cellular processes, with a focus on the NAD+ interplay and the modulation of the...

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Principais autores: Hojun Lee, Haejin Yoon
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-02-01
Serier:Molecules and Cells
Fag:
Cancer metabolism
Mitochondrial sirtuins
Mitochondria metabolism
NAD+
SIRT3
Online adgang:http://www.sciencedirect.com/science/article/pii/S1016847824000347
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