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SSNA1 stabilizes dynamic microtubules and detects microtubule damage

Sjögren’s syndrome nuclear autoantigen-1 (SSNA1/NA14) is a microtubule-associated protein with important functions in cilia, dividing cells, and developing neurons. However, the direct effects of SSNA1 on microtubules are not known. We employed in vitro reconstitution with purified proteins and TIRF...

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Autori principali: Elizabeth J Lawrence, Goker Arpag, Cayetana Arnaiz, Marija Zanic
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications Ltd 2021-12-01
Serie:eLife
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Accesso online:https://elifesciences.org/articles/67282
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