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Evaluation of Rhenium and Technetium-99m Complexes Bearing Quinazoline Derivatives as Potential EGFR Agents

Τhe Epidermal Growth Factor Receptor tyrosine kinase inhibitor (EGFR-TKI) 6-amino-4-[(3-bromophenyl) amino]quinazoline was derivatized with 6-bromohexanoyl-chloride and coupled with the tridentate chelating agents N-(2-pyridylmethyl) aminoethyl acetic acid (PAMA) and <i>L</i>(+)-cysteine bearing the...

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Principais autores: Konstantina Makrypidi, Christos Kiritsis, Ioanna Roupa, Sotiria Triantopoulou, Antonio Shegani, Maria Paravatou-Petsotas, Aristeidis Chiotellis, Maria Pelecanou, Minas Papadopoulos, Ioannis Pirmettis
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-02-01
Serier:Molecules
Fag:
EGFR
TKI
PAMA
cysteine
rhenium
technetium-99m
Online adgang:https://www.mdpi.com/1420-3049/28/4/1786
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