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The evolving hematopoietic niche during development

Mammalian hematopoietic stem cells (HSCs) emerge from the hemogenic endothelium in the major embryonic arteries. HSCs undergo a complex journey first migrating to the fetal liver (FL) and from there to the fetal bone marrow (FBM), where they mostly remain during adult life. In this process, a pool o...

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Principais autores: Raúl Sánchez-Lanzas, Amanda Jiménez-Pompa, Miguel Ganuza
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-10-01
Serier:Frontiers in Molecular Biosciences
Fag:
hematopoietic stem cells
developmental hematopoiesis
hematopoietic niches
aorta-gonad-mesonephros
fetal liver
bone marrow
Online adgang:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1488199/full
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