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Mechanisms of astrocyte aging in reactivity and disease

Abstract Normal aging alters brain functions and phenotypes. However, it is not well understood how astrocytes are impacted by aging, nor how they contribute to neuronal dysfunction and disease risk as organisms age. Here, we examine the transcriptional, cell biology, and functional differences in a...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Holly K. Gildea, Shane A. Liddelow
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-02-01
Schriftenreihe:Molecular Neurodegeneration
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Online-Zugang:https://doi.org/10.1186/s13024-025-00810-7
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