Hepatic safety of repeated treatment with pyronaridine‐artesunate versus artemether–lumefantrine in patients with uncomplicated malaria: a secondary analysis of the WANECAM 1 data from Bobo-Dioulasso, Burkina Faso

Abstract Background The use of pyronaridine-artesunate (PA) has been associated with scarce transaminitis in patients. This analysis aimed to evaluate the hepatic safety profile of repeated treatment with PA versus artemether–lumefantrine (AL) in patients with consecutive uncomplicated malaria episo...

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主要な著者:	Yves Daniel Compaoré, Issaka Zongo, Anyirékun F. Somé, Nouhoun Barry, Frederick Nikiéma, Talato N. Kaboré, Aminata Ouattara, Zachari Kabré, Kadidiatou Wermi, Moussa Zongo, Rakiswende S. Yerbanga, Issaka Sagara, Abdoulaye Djimdé, Jean Bosco Ouédraogo
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2021-01-01
シリーズ:	Malaria Journal
主題:	Repeated treatment Pyronaridine‐artesunate Artemether–lumefantrine Uncomplicated malaria Hepatoxicity Hy’s law
オンライン･アクセス:	https://doi.org/10.1186/s12936-021-03593-6
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