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Identifying actionable druggable targets for breast cancer: Mendelian randomization and population-based analysesResearch in context

Summary: Background: Drug repurposing provides a cost-effective approach to address the need for breast cancer prevention and therapeutics. We aimed to identify actionable druggable targets using Mendelian randomization (MR) and then validate the candidate drugs using population-based analyses. Met...

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Principais autores: Naiqi Zhang, Yanni Li, Jan Sundquist, Kristina Sundquist, Jianguang Ji
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2023-12-01
Serier:EBioMedicine
Fag:
Drug repositioning
Breast cancer
Druggable target
Mendelian randomization
Population-based study
Online adgang:http://www.sciencedirect.com/science/article/pii/S2352396423004255
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