Intracellular persistence of Staphylococcus aureus in endothelial cells is promoted by the absence of phenol-soluble modulins

A large proportion of clinical S. aureus isolates that carry an inactive Agr system are associated with persistent infection that is difficult to treat. Once S. aureus is inside the bloodstream, it can cross the endothelial barrier and invade almost every organ in the human body. Endothelial cells c...

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Bibliografische Detailangaben

Hauptverfasser:	Anke Siegmund, Muhammad Awais Afzal, Felix Tetzlaff, Daniela Keinhörster, Fabio Gratani, Kerstin Paprotka, Martin Westermann, Sandor Nietzsche, Christiane Wolz, Martin Fraunholz, Christian A. Hübner, Bettina Löffler, Lorena Tuchscherr
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2021-12-01
Schriftenreihe:	Virulence
Schlagworte:	staphylococcus aureus intracellular persistence phenol-soluble modulins lc3-vesicles chronic infections
Online-Zugang:	http://dx.doi.org/10.1080/21505594.2021.1910455
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