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Cyclooxygenase-2 inhibition attenuates abdominal aortic aneurysm progression in hyperlipidemic mice.

Abdominal aortic aneurysms (AAAs) are a chronic inflammatory disease that increase the risk of life-threatening aortic rupture. In humans, AAAs have been characterized by increased expression of cyclooxygenase-2 and the inactivation of COX-2 prior to disease initiation reduces AAA incidence in a mou...

詳細記述

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書誌詳細
主要な著者: Sarbani Ghoshal, Charles D Loftin
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2012-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC3507882?pdf=render
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