Copper Induces Protein Aggregation, a Toxic Process Compensated by Molecular Chaperones

ABSTRACT Copper is well known for its antimicrobial and antiviral properties. Under aerobic conditions, copper toxicity relies in part on the production of reactive oxygen species (ROS), especially in the periplasmic compartment. However, copper is significantly more toxic under anaerobic conditions...

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Detalhes bibliográficos

Principais autores:	Lisa Zuily, Nora Lahrach, Rosi Fassler, Olivier Genest, Peter Faller, Olivier Sénèque, Yann Denis, Marie-Pierre Castanié-Cornet, Pierre Genevaux, Ursula Jakob, Dana Reichmann, Marie-Thérèse Giudici-Orticoni, Marianne Ilbert
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2022-04-01
coleção:	mBio
Assuntos:	copper stress molecular chaperone protein aggregation copper homeostasis Escherichia coli DnaK
Acesso em linha:	https://journals.asm.org/doi/10.1128/mbio.03251-21
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