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Spatio-temporal control of mitosis using light via a Plk1 inhibitor caged for activity and cellular permeability

Abstract The ability to control the activity of kinases spatially and temporally is essential to elucidate the role of signalling pathways in development and physiology. Progress in this direction has been hampered by the lack of tools to manipulate kinase activity in a highly controlled manner in v...

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Principais autores: Victoria von Glasenapp, Ana C. Almeida, Dalu Chang, Ivana Gasic, Nicolas Winssinger, Monica Gotta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2025-02-01
coleção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-025-56746-5
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