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N6-methyladenosine regulates metabolic remodeling in kidney aging through transcriptional regulator GLIS1

Abstract Background Age-related kidney impairment, characterized by tubular epithelial cell senescence and renal fibrosis, poses a significant global public health threat. Although N6-methyladenosine (m6A) methylation is implicated in various pathological processes, its regulatory mechanism in kidne...

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Huvudupphov: Li Xu, Shuo Chen, Qiuling Fan, Yonghong Zhu, Hang Mei, Jiao Wang, Hongyuan Yu, Ying Chen, Fan Liu
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMC 2024-12-01
Serie:BMC Biology
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Länkar:https://doi.org/10.1186/s12915-024-02100-y
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