Mucus plugging on computed tomography and the sputum microbiome in patients with asthma, chronic obstructive pulmonary disease, and asthma-COPD overlap

Background: Despite clinical implications, the pathogenesis of mucus plugging in asthma, chronic obstructive pulmonary disease (COPD), and asthma-COPD overlap (ACO) remains unclear. We hypothesized that distinct airway microbiomes might affect mucus plugging differently among ACO, asthma, and COPD a...

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Autori principali:	Naoya Tanabe, Hisako Matsumoto, Chie Morimoto, Yusuke Hayashi, Ryo Sakamoto, Tsuyoshi Oguma, Tadao Nagasaki, Hironobu Sunadome, Atsuyasu Sato, Susumu Sato, Kai Ohashi, Takamitsu Tsukahara, Toyohiro Hirai
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-10-01
Serie:	Allergology International
Soggetti:	Asthma-COPD overlap Airway inflammation Computed tomography Microbiome Mucus
Accesso online:	http://www.sciencedirect.com/science/article/pii/S1323893024000558
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