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Sequence features and transcriptional stalling within centromere DNA promote establishment of CENP-A chromatin.

Centromere sequences are not conserved between species, and there is compelling evidence for epigenetic regulation of centromere identity, with location being dictated by the presence of chromatin containing the histone H3 variant CENP-A. Paradoxically, in most organisms CENP-A chromatin generally o...

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Autors principals: Sandra Catania, Alison L Pidoux, Robin C Allshire
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2015-03-01
Col·lecció:PLoS Genetics
Accés en línia:http://europepmc.org/articles/PMC4349457?pdf=render
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