Small molecules facilitate single factor-mediated sweat gland cell reprogramming

Abstract Background Large skin defects severely disrupt the overall skin structure and can irreversibly damage sweat glands (SG), thus impairing the skin’s physiological function. This study aims to develop a stepwise reprogramming strategy to convert fibroblasts into SG lineages, which may provide...

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Autors principals:	Shuai-Fei Ji, Lai-Xian Zhou, Zhi-Feng Sun, Jiang-Bing Xiang, Shao-Yuan Cui, Yan Li, Hua-Ting Chen, Yi-Qiong Liu, Huan-Huan Gao, Xiao-Bing Fu, Xiao-Yan Sun
Format:	Artigo
Idioma:	Inglês
Publicat:	KeAi Communications Co., Ltd. 2022-03-01
Col·lecció:	Military Medical Research
Matèries:	Direct reprogramming Human dermal fibroblasts Sweat gland Regeneration
Accés en línia:	https://doi.org/10.1186/s40779-022-00372-5
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