Biochemical and genetic analysis of butyrylcholinesterase (BChE) in a family, due to prolonged neuromuscular blockade after the use of succinylcholine

Butyrylcholinesterase (BChE) is a plasma enzyme that catalyzes the hydrolysis of choline esters, including the muscle-relaxant succinylcholine and mivacurium. Patients who present sustained neuromuscular blockade after using succinylcholine usually carry BChE variants with reduced enzyme activity or...

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Detalhes bibliográficos

Principais autores:	Daniel Fantozzi Garcia, Ticiano G. Oliveira, Greice A. Molfetta, Luiz V. Garcia, Cristiane A. Ferreira, Adriana A. Marques, Wilson Araujo Silva Jr.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Sociedade Brasileira de Genética 2011-01-01
coleção:	Genetics and Molecular Biology
Assuntos:	hereditary hypocholinesterasemia butyrylcholinesterase succinylcholine BCHE gene DNA polymorphism
Acesso em linha:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000100008
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