DLG1 functions upstream of SDCCAG3 and IFT20 to control ciliary targeting of polycystin-2

Abstract Polarized vesicular trafficking directs specific receptors and ion channels to cilia, but the underlying mechanisms are poorly understood. Here we describe a role for DLG1, a core component of the Scribble polarity complex, in regulating ciliary protein trafficking in kidney epithelial cell...

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Detalhes bibliográficos

Principais autores:	Csenge K Rezi, Mariam G Aslanyan, Gaurav D Diwan, Tao Cheng, Mohamed Chamlali, Katrin Junger, Zeinab Anvarian, Esben Lorentzen, Kleo B Pauly, Yasmin Afshar-Bahadori, Eduardo FA Fernandes, Feng Qian, Sébastien Tosi, Søren T Christensen, Stine F Pedersen, Kristian Strømgaard, Robert B Russell, Jeffrey H Miner, Moe R Mahjoub, Karsten Boldt, Ronald Roepman, Lotte B Pedersen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer Nature 2024-06-01
coleção:	EMBO Reports
Assuntos:	DLG1 Primary Cilia SDCCAG3 IFT20 Polycystin-2
Acesso em linha:	https://doi.org/10.1038/s44319-024-00170-1
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