Influenza A virus hemagglutinin mutations associated with use of neuraminidase inhibitors correlate with decreased inhibition by anti-influenza antibodies

Abstract Background Vaccination and the use of neuraminidase inhibitors (NAIs) are currently the front lines of defense against seasonal influenza. The activity of influenza vaccines and antivirals drugs such as the NAIs can be affected by mutations in the influenza hemagglutinin (HA) protein. Numer...

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Главные авторы:	Natalia A. Ilyushina, Takashi E. Komatsu, William L. Ince, Eric F. Donaldson, Nicolette Lee, Julian J. O’Rear, Raymond P. Donnelly
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2019-11-01
Серии:	Virology Journal
Предметы:	Hemagglutinin (HA) Neuraminidase (NA) Neuraminidase inhibitors (NAI) Influenza A virus Antiviral resistance
Online-ссылка:	https://doi.org/10.1186/s12985-019-1258-x
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