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TAPBPR mediates peptide dissociation from MHC class I using a leucine lever

Tapasin and TAPBPR are known to perform peptide editing on major histocompatibility complex class I (MHC I) molecules; however, the precise molecular mechanism(s) involved in this process remain largely enigmatic. Here, using immunopeptidomics in combination with novel cell-based assays that assess...

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Hlavní autoři: F Tudor Ilca, Andreas Neerincx, Clemens Hermann, Ana Marcu, Stefan Stevanović, Janet E Deane, Louise H Boyle
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications Ltd 2018-11-01
Edice:eLife
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On-line přístup:https://elifesciences.org/articles/40126
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