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Single-cell chromatin accessibility profiling of cell-state-specific gene regulatory programs during mouse organogenesis

In mammals, early organogenesis begins soon after gastrulation, accompanied by specification of various type of progenitor/precusor cells. In order to reveal dynamic chromatin landscape of precursor cells and decipher the underlying molecular mechanism driving early mouse organogenesis, we performed...

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Principais autores: Qiuting Deng, Shengpeng Wang, Zijie Huang, Qing Lan, Guangyao Lai, Jiangshan Xu, Yue Yuan, Chang Liu, Xiumei Lin, Weimin Feng, Wen Ma, Mengnan Cheng, Shijie Hao, Shanshan Duan, Huiwen Zheng, Xiaoyan Chen, Yong Hou, Yingjie Luo, Longqi Liu, Chuanyu Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-06-01
coleção:Frontiers in Neuroscience
Assuntos:
mouse organogenesis
single-cell ATAC-seq
spinal cord
paraxial mesoderm
cis-regulatory elements
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnins.2023.1170355/full
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