Glycolytic heterogeneity drives metabolic-targeted therapy in pancreatic ductal adenocarcinoma

Abstract Pancreatic ductal adenocarcinoma is traditionally characterized as a glycolytic tumor. However, the extent and clinical relevance of its metabolic heterogeneity remain poorly understood. In this study, we investigated whether glycolytic activity follows a consistent expression pattern acros...

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Bibliografiske detaljer

Principais autores:	Ugo Chianese, Chiara Papulino, Gerardo Saggese, Ahmad Ali, Marianna Ciotola, Enza Lonardo, Mirko Cortese, Gregorio Favale, Annabella Di Mauro, Danila La Gioia, Valentina Golino, Eduardo Sommella, Pietro Campiglia, Renato Franco, Fortunato Ciardiello, Ferdinando De Vita, Vincenzo Carafa, Lucia Altucci, Rosaria Benedetti
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2026-01-01
Serier:	Signal Transduction and Targeted Therapy
Online adgang:	https://doi.org/10.1038/s41392-025-02546-8
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