Potential molecular mechanisms of ETV6-RUNX1-positive B progenitor cell cluster in acute lymphoblastic leukemia revealed by single-cell RNA sequencing

Aim This study was to explore role of immune landscape and the immune cells in acute lymphoblastic leukemia (ALL) progression. Background The most prevalent genetic alteration in childhood ALL is the ETV6-RUNX1 fusion. The increased proliferation of B progenitor cells could expedite the disease’s pr...

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Auteurs principaux:	Ning Qu, Yue Wan, Xin Sui, Tianyi Sui, Yang Yang
Format:	Artigo
Langue:	Inglês
Publié:	PeerJ Inc. 2024-11-01
Collection:	PeerJ
Sujets:	ETV6-RUNX1 Acute lymphoblastic leukemia Immune landscape B progenitor cells Chromosome amplification Cell cycle
Accès en ligne:	https://peerj.com/articles/18445.pdf
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