“Three-birds-one-stone” environment responsive delivery system with tumor microenvironment remodeling to enhance solid tumor therapy

Abstract Unique tumor microenvironment (TME), tumor cell reprogramming and tumor tissues wrapped by rigid extracellular matrix (ECM), these natural physiological barriers can compromise solid tumor treatment. In this study, we constructed a “three-birds-one-stone” delivery system (PEG-MnO2/ZIF/DOX&N...

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Auteurs principaux:	Chunmin Deng, Dong Shen, Mengyi Li, Changsong Zhang, Qingzhen Wang
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2026-01-01
Collection:	Cancer Nanotechnology
Sujets:	Tumor microenvironment Extracellular matrix Environment responsive Tumor-associated fibroblasts
Accès en ligne:	https://doi.org/10.1186/s12645-026-00368-z
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