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Blockade of Autophagy Prevents the Progression of Hyperuricemic Nephropathy Through Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis

Hyperuricemia has become a common metabolic disease, and is a risk factor for multiple diseases, including chronic kidney disease. Our recent study indicated that following persistent uric acid stimulation, autophagy was activated in rats of hyperuricemic nephropathy (HN) and facilitated the develop...

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Bibliografische Detailangaben
Hauptverfasser: Yan Hu, Yingfeng Shi, Hui Chen, Min Tao, Xun Zhou, Jinqing Li, Xiaoyan Ma, Yi Wang, Na Liu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2022-03-01
Schriftenreihe:Frontiers in Immunology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2022.858494/full
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