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Identification and functional characterization of novel phosphorylation sites in TAK1-binding protein (TAB) 1.

TAB1 was defined as a regulatory subunit of the protein kinase TAK1, which functions upstream in the pathways activated by interleukin (IL)-1, tumor necrosis factor (TNF), toll-like receptors (TLRs) and stressors. However, TAB1 also functions in the p38 MAPK pathway downstream of TAK1. We identified...

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Principais autores: Alexander Wolf, Knut Beuerlein, Christoph Eckart, Hendrik Weiser, Beate Dickkopf, Helmut Müller, Hiroaki Sakurai, Michael Kracht
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2011-01-01
Serier:PLoS ONE
Online adgang:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22216226/?tool=EBI
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