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Angelic Acid Prevents RANKL-Induced Osteoclastogenesis Through Pathway-Biased Inhibition of MAPK–NFATc1 Signaling

Excessive osteoclast activity drives inflammatory bone loss in osteoporosis, rheumatoid arthritis, and periodontitis. Natural compounds represent promising therapeutic candidates with favorable safety profiles; however, few exhibit pathway-biased mechanisms of action. Here, we report that angelic ac...

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Principais autores: Lifang Zhang, Mojtaba Tabandeh, Vishwa Deepak
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2026-04-01
סדרה:Current Issues in Molecular Biology
נושאים:
angelic acid
osteoclast
RANKL
MAPK
natural product
bone resorption
גישה מקוונת:https://www.mdpi.com/1467-3045/48/4/412
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