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Reinvigorating AMR resilience: leveraging CRISPR–Cas technology potentials to combat the 2024 WHO bacterial priority pathogens for enhanced global health security—a systematic review

Abstract Background Antimicrobial resistance (AMR) poses a global health threat, particularly in low- and middle-income countries (LMICs). Clustered regularly interspaced short palindromic repeats (CRISPR)–Cas system technology offers a promising tool to combat AMR by targeting and disabling resista...

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Hauptverfasser: Olalekan John Okesanya, Mohamed Mustaf Ahmed, Jerico Bautista Ogaya, Blessing Olawunmi Amisu, Bonaventure Michael Ukoaka, Olaniyi Abideen Adigun, Emery Manirambona, Olakulehin Adebusuyi, Zhinya Kawa Othman, Olanegan Gloria Oluwakemi, Oluwaseunayo Deborah Ayando, Maria Ivy Rochelle S. Tan, Nimat Bola Idris, Hassan Hakeem Kayode, Tolutope Adebimpe Oso, Musa Ahmed, M. B. N. Kouwenhoven, Adamu Muhammad Ibrahim, Don Eliseo Lucero-Prisno
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-04-01
Schriftenreihe:Tropical Medicine and Health
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Online-Zugang:https://doi.org/10.1186/s41182-025-00728-2
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