Tumor-associated macrophages educated by IGSF9 exhibit a senescence-associated secretory phenotype to promote tumor immune escape

Background IGSF9, immunoglobulin superfamily member 9, has been reported to inhibit T cell proliferation and activation, thereby promoting tumor immune escape. Tumor-associated macrophages (TAMs), the most abundant tumor-infiltrating immune cells, play a crucial role in forming the immunosuppressive...

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Autori principali:	Ting Wang, Fang Li, Xinyu Zhao, Hongying Wang, Hong Yu, Chunling Li, Jiasheng Zhang, Xianhui Meng, Huiwen Luan, Fangmin Li, Yuxiao Sun, Guantong Liu, Yingxin Pang, Aihui Xu, Lijun Hui, Shuping Wei, Yaopeng Wang, Zunling Li
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMJ Publishing Group 2026-01-01
Serie:	Journal for ImmunoTherapy of Cancer
Accesso online:	https://jitc.bmj.com/content/14/1/e012889.full
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