Polychlorinated Biphenyl 138 Induces Toxicant-Associated Steatohepatitis via Hepatic Iron Overload and Adipose Inflammation

Toxicant-associated steatohepatitis (TASH) is caused by environmental toxicants rather than metabolic factors; however, its pathogenic mechanisms remain poorly understood. Polychlorinated biphenyl 138 (PCB138), a persistent lipophilic contaminant that bioaccumulates in adipose tissue, may promote TA...

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Autori principali:	Hyeon Jeong Hwang, Mi Hwa Lee, Seung Hui Lee, Byung-Jun Sung, Joong-Gook Kim, Dae Yun Seo, Dae Young Hur, Young Hyun Yoo, JaeHun Cheong, Hye Young Kim
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-10-01
Serie:	Toxics
Soggetti:	PCB138 TASH iron–adipose axis hepcidin ferroportin adipose inflammation
Accesso online:	https://www.mdpi.com/2305-6304/13/11/932
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