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Cholesterol dependence of collagen and echovirus 1 trafficking along the novel α2β1 integrin internalization pathway.

We have previously shown that soluble collagen and a human pathogen, echovirus 1 (EV1) cluster α2β1 integrin on the plasma membrane and cause their internalization into cytoplasmic endosomes. Here we show that cholesterol plays a major role not only in the uptake of α2β1 integrin and its ligands but...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Elina Siljamäki, Nina Rintanen, Maija Kirsi, Paula Upla, Wei Wang, Mikko Karjalainen, Elina Ikonen, Varpu Marjomäki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2013-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23393580/pdf/?tool=EBI
Tagiau: Ychwanegu Tag
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