Dysbiotic shift in the oral microbiota of patients with Alzheimer's disease compared to their healthy life partners—a combinatorial approach and a paired study design

Abstract Background The oral microbiota has been associated with Alzheimer's disease (AD). However, earlier studies provided conflicting results using varying sampling methods, sequencing techniques, and statistics, as well as independent subjects. Methods To robustly identify disease-associated mic...

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Hlavní autoři:	Christian Weber, Daniel Wind, Patrick Petzsch, Tillmann Supprian, Alexander Dilthey, Julia Christl, Patrick Finzer
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2026-01-01
Edice:	Alzheimer’s Research & Therapy
Témata:	Alzheimer Dementia Spouses Oral microbiota Next generation sequencing Periodontal disease
On-line přístup:	https://doi.org/10.1186/s13195-025-01941-1
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