High Interferon-γ Uniquely in Vδ1 T Cells Correlates with Markers of Inflammation and Axonal Damage in Early Multiple Sclerosis

We have identified a population of T lymphocytes in peripheral blood, Vδ1 TCRγδ T lymphocytes, which unexpectedly was uniquely expressing high production of interferon-γ in newly diagnosed, untreated multiple sclerosis (MS) patients. IFN-γ production in this population distinctly correlated to param...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Avadhesh Kumar Singh, Lenka Novakova, Markus Axelsson, Clas Malmeström, Henrik Zetterberg, Jan Lycke, Susanna L. Cardell
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2017-03-01
coleção:	Frontiers in Immunology
Assuntos:	cerebrospinal fluid gamma-delta T cells interferon-gamma multiple sclerosis natalizumab Vdelta1 T cells
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00260/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!