Genetic Variation Putatively Associated with <i>Mycobacterium tuberculosis</i> Resistance to Perchlozone, a New Thiosemicarbazone: Clues from Whole Genome Sequencing and Implications for Treatment of Multidrug-Resistant Tuberculosis
Perchlozone ([PCZ] 4-thioureido-iminomethylpyridinium perchlorate) is a new thiosemicarbazone approved for the treatment of multidrug-resistant tuberculosis (MDR-TB) in Russia and some other countries. The <i>ethA</i> and <i>hadABC</i> mutations may confer PCZ resistance. At the same time, <i>ethA</...
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| Автори: | , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
MDPI AG
2020-10-01
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| Серія: | Antibiotics |
| Предмети: | |
| Онлайн доступ: | https://www.mdpi.com/2079-6382/9/10/669 |
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