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IL-1β-activated PI3K/AKT and MEK/ERK pathways coordinately promote induction of partial epithelial–mesenchymal transition

Abstract Epithelial–mesenchymal transition (EMT) is a cellular process in embryonic development, wound healing, organ fibrosis, and cancer metastasis. Previously, we and others have reported that proinflammatory cytokine interleukin-1β (IL-1β) induces EMT. However, the exact mechanisms, especially t...

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Bibliografiske detaljer
Principais autores: Yosuke Tabei, Yoshihiro Nakajima
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-08-01
Serier:Cell Communication and Signaling
Fag:
Online adgang:https://doi.org/10.1186/s12964-024-01775-8
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