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Comparative development of human filariae Loa loa, Onchocerca volvulus and Mansonella perstans in immunocompromised mouse strains

IntroductionMouse models of human filarial infections are not only urgently needed to investigate the biology of the nematodes and their modulation of the host’s immunity, but will also provide a platform to screen and test novel anti-filarial drugs. Recently, murine Loa loa infection models have be...

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Principais autores: Valerine C. Chunda, Fanny Fri Fombad, Chi Anizette Kien, Rene Ebai, Frederick Esofi, Anna Ning Ntuh, Emmanuel Ouam, Narcisse Victor Tchamatchoua Gandjui, Relindis Ekanya, Franck Nietcho, Lucy Cho Nchang, Chefor Magha, Abdel Jelil Njouendou, Peter Enyong, Achim Hoerauf, Samuel Wanji, Manuel Ritter
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-04-01
Serier:Frontiers in Tropical Diseases
Fag:
Mansonella perstans
Loa loa
Onchocerca volvulus
murine models of human filariasis
immunocompromised mice
Online adgang:https://www.frontiersin.org/articles/10.3389/fitd.2024.1293632/full
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