Enhanced extracellular production of Coprinopsis cinerea laccase Lcc9 in Aspergillus niger by gene expression cassette and bioprocess optimization

Abstract Background The laccase Lcc9 from Coprinopsis cinerea has optimal catalytic activity at moderate to alkaline pH conditions, making it invaluable for industrial applications. However, C. cinerea naturally secretes Lcc9 at low expression levels, which limits the industrial application of Lcc9...

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Autores principales:	Dongbang Yao, Xiaozhuang Liu, Hui Wang, Juanjuan Liu, Zemin Fang, Yazhong Xiao
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2024-11-01
Colección:	BMC Biotechnology
Materias:	Laccase Aspergillus niger Signal peptide Promoter Integration loci Bioprocess
Acceso en línea:	https://doi.org/10.1186/s12896-024-00924-8
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