ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

ABSTRACT While Fgf and Hippo‐Yap signaling are fundamental for proper development, homeostasis, and disease, their crosstalk remains largely unknown. Here, we identified that Yap and Taz, canonical Hippo effectors, function as noncanonical effectors of Fgf signaling to maintain the proper function o...

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Autors principals:	Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2026-07-01
Col·lecció:	Advanced Science
Matèries:	ERK FGF signaling neural crest cell suture mesenchymal cells YAP
Accés en línia:	https://doi.org/10.1002/advs.202511484
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