Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome

Objective: The Allan-Herndon-Dudley syndrome (AHDS) is a severe disease caused by dysfunctional central thyroid hormone transport due to functional loss of the monocarboxylate transporter 8 (MCT8). In this study, we assessed whether mice with concomitant deletion of the thyroid hormone transporters...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Gandhari Maity-Kumar, Lisa Ständer, Meri DeAngelis, Sooyeon Lee, Anna Molenaar, Lore Becker, Lillian Garrett, Oana V. Amerie, Sabine M. Hoelter, Wolfgang Wurst, Helmut Fuchs, Annette Feuchtinger, Valerie Gailus-Durner, Cristina Garcia-Caceres, Ahmed E. Othman, Caroline Brockmann, Vanessa I. Schöffling, Katja Beiser, Heiko Krude, Piotr A. Mroz, Susanna Hofmann, Jan Tuckermann, Richard D. DiMarchi, Martin Hrabe de Angelis, Matthias H. Tschöp, Paul T. Pfluger, Timo D. Müller
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2022-12-01
Serie:	Molecular Metabolism
Soggetti:	Allan-Herndon Dudley Syndrome Thyroid hormone Mct8 Oatp1c1 Energy metabolism Myelination
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2212877822001855
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!