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Differential Regulation of Thyroid Hormone Metabolism Target Genes during Non-thyroidal Illness Syndrome Triggered by Fasting or Sepsis in Adult Mice

Fasting and sepsis induce profound changes in thyroid hormone (TH) central and peripheral metabolism. These changes affect TH action and are called the non-thyroidal illness syndrome (NTIS). To date, it is still debated whether NTIS represents an adaptive response or a real hypothyroid state at the...

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Principais autores: Klaus N. Fontes, Adriana Cabanelas, Flavia F. Bloise, Cherley Borba Vieira de Andrade, Luana L. Souza, Marianna Wilieman, Isis H. Trevenzoli, Lais C. Agra, Johnatas D. Silva, Christianne Bandeira-Melo, Pedro L. Silva, Patricia R. M. Rocco, Tania M. Ortiga-Carvalho
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017-10-01
coleção:Frontiers in Physiology
Assuntos:
non-thyroidal illness syndrome
thyroid hormones
fasting
sepsis
CLP
thyroid hormone metabolism
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fphys.2017.00828/full
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