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Phage Henu15-resistant mutant derives fitness trade-offs in Morganella morganii

Abstract The rapid emergence of multidrug-resistant strains of Morganella necessitates new therapeutic approaches, such as phage therapy. Phages are considered a promising adjunct to antibiotics. However, the rapid emergence of phage-resistant bacterial mutants poses a significant challenge in clini...

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Principais autores: Yuhan Wang, Jiawen Shen, Hanyue Zhuang, Huiru Cao, Jingjing Li, Xiaoxue Yang, Fangyuan Liu, Qian Wang, Jiajia Xie, Jiayi Geng, Waner Wang, Yueting Xi, Xiaoqing Wang, Qiming Li, Tieshan Teng
Format: Artigo
Sprog:Inglês
Udgivet: SpringerOpen 2026-03-01
Serier:AMB Express
Fag:
Morganella morganii
Antimicrobial resistance
Phage
Synergy
Phage-resistant
Fitness trade-offs
Online adgang:https://doi.org/10.1186/s13568-026-02032-6
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