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Hsd17b7 undergoes dynamic subcellular localization during Neuro2a differentiation

Enzymes within the cholesterol biosynthesis pathway, particularly those in post-squalene biosynthesis, have been linked to abnormal neurodevelopment. Alterations of individual enzymes manifest unique brain phenotypes, suggesting each enzyme has distinct roles within the mammalian neural cell. Howeve...

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Auteurs principaux: Matthew Bispo, Macey Pennay, Joe C. Brague, Ashley M. Driver
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2026-01-01
Collection:Frontiers in Molecular Neuroscience
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fnmol.2025.1639803/full
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