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A bilayered microneedle patch loaded with methotrexate and dexamethasone for transdermal treatment of psoriasis

Abstract Psoriasis is a persistent inflammatory dermatological disorder characterized by dysregulated hyperproliferation of keratinocytes and pathological immune cell infiltration, impacting a significant population globally. Conventional systemic therapies, including oral and injectable formulation...

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Principais autores: Ting Wang, Die Li, Haojie Bi, Yi Liu, Xuan Xu, Hanying Wang, Qianwei Jin, Shaochun Chen, Lechun Lyu, Jingpei Shi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2026-02-01
Series:Scientific Reports
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Acceso en liña:https://doi.org/10.1038/s41598-026-38216-0
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