PCNA Deubiquitylases Control DNA Damage Bypass at Replication Forks
Summary: DNA damage tolerance plays a key role in protecting cell viability through translesion synthesis and template switching-mediated bypass of genotoxic polymerase-blocking base lesions. Both tolerance pathways critically rely on ubiquitylation of the proliferating-cell nuclear antigen (PCNA) o...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2019-10-01
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| Serie: | Cell Reports |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2211124719312422 |
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