Increased LDL receptor by SREBP2 or SREBP2-induced lncRNA LDLR-AS promotes triglyceride accumulation in fish

Summary: LDLR, as the uptake receptor of low-density lipoprotein, plays a crucial role in lipid metabolism. However, the detailed mechanism by which LDLR affects hepatic triglyceride (TG) accumulation has rarely been reported. Here, we found that knockdown of LDLR effectively mitigated PA-induced TG...

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Principais autores:	Xiufei Cao, Wei Fang, Xueshan Li, Xiuneng Wang, Kangsen Mai, Qinghui Ai
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2022-07-01
叢編:	iScience
主題:	Biological sciences Zoology Cell biology Functional aspects of cell biology
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2589004222009427
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