The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus

Summary: Radial glia-like (RGL) stem cells persist in the adult mammalian hippocampus, where they generate new neurons and astrocytes throughout life. The process of adult neurogenesis is well documented, but cell-autonomous factors regulating neuronal and astroglial differentiation are incompletely...

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Bibliografiska uppgifter

Huvudupphov:	Bhavana Gupta, Adam C. Errington, Ana Jimenez-Pascual, Vasileios Eftychidis, Simone Brabletz, Marc P. Stemmler, Thomas Brabletz, David Petrik, Florian A. Siebzehnrubl
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Elsevier 2021-08-01
Serie:	Cell Reports
Ämnen:	neural stem cell EMT asymmetrical division gliogenesis Cre-loxP lineage specification
Länkar:	http://www.sciencedirect.com/science/article/pii/S2211124721010226
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