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Rhotekin regulates axon regeneration through the talin-Vinculin-Vinexin axis in Caenorhabditis elegans.

Axon regeneration requires actomyosin interaction, which generates contractile force and pulls the regenerating axon forward. In Caenorhabditis elegans, TLN-1/talin promotes axon regeneration through multiple down-stream events. One is the activation of the PAT-3/integrin-RHO-1/RhoA GTPase-LET-502/R...

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Bibliografische gegevens
Hoofdauteurs: Yoshiki Sakai, Tatsuhiro Shimizu, Mayuka Tsunekawa, Naoki Hisamoto, Kunihiro Matsumoto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2023-12-01
Reeks:PLoS Genetics
Online toegang:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011089&type=printable
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